Case report of glanzmann thrombasthenia medical student. Treatment for glanzmanns thrombasthenia glanzmanns. Glanzmann thrombasthenia was discovered in berne, switzerland in 1918 by a pediatrician named glanzmann. It is an extremely rare coagulopathy bleeding disorder due to a blood abnormality, in which the platelets contain defective or low levels of glycoprotein iibiiia gpiibiiia, which is a receptor for fibrinogen. There are many dangers of continual bleeding such as chronic anemia, neurological or psychiatric problems, and possibly death, if enough.
Anyone with a bleeding disorder should avoid taking aspirin and other nonsteroidal antiinflammatory drugs nsaids such as ibuprofen and naproxen. There are many dangers of continual bleeding such as chronic anemia, neurological or psychiatric problems, and possibly death, if. Birth control pills may help some women with gt who have very heavy periods for severe bleeding, people with gt may be given platelets from a blood donor. In this village there were frequent marriages between close relatives. Glanzmanns thrombasthenia is an abnormality of the platelets. Fredy glanzmann born 1963, swiss nordic combined skier. Glanzmanns disease is a longterm disorder with no cure. The children affected by the disease all came from a tiny village, called le valais, situated high in the swiss alps. Anyone with a bleeding disorder should avoid taking aspirin and other nonsteroidal antiinflammatory drugs nsaids such as. It it can occur as petechiae, epistaxis and gastrointestinal and gingival bleeding. Abstract glanzmanns thrombasthenia gt is a low frequency hematologic disease with an autosomal recessive inheritance pattern. A problem can happen because the donors platelets will have gpiib iiia and the person with gts platelets do not. Case a 19yearold arab descent female presented to emergency department with severe menorrhagia. Glanzmann s thrombasthenia is an abnormality of the platelets.
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